Altering human DNA

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Altering human DNA

Postby BadgerJelly on November 15th, 2017, 6:46 am 

Scientists for the first time have tried editing a gene inside the body in a bold attempt to permanently change a person’s DNA to try to cure a disease.


https://www.msn.com/en-gb/news/techandscience/scientists-have-made-their-first-attempt-at-gene-editing-inside-a-human-patient/ar-BBEYUjW?li=AAmiR2Z&ocid=spartanntp

Signs of whether it’s working may come in a month; tests will show for sure in three months.
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Re: Altering human DNA

Postby BioWizard on November 15th, 2017, 8:23 am 

For the first time? I don’t think so.
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Re: Altering human DNA

Postby BioWizard on November 15th, 2017, 9:09 am 

Taking a closer look, this is the novel part:

"This time, the gene tinkering is happening in a precise way inside the body. It’s like sending a mini surgeon along to place the new gene in exactly the right location."

So the editing is being done directly, inside the patient's body.

Pretty cool.
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Re: Altering human DNA

Postby BadgerJelly on November 15th, 2017, 9:11 am 

Thanks for clarification. Remind me in a few months if I forget to check up on this (then again I would guess it will be all over the news if anything dramatic happens!)

Then the ethical debate will gain more heat.
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Re: Altering human DNA

Postby BioWizard on November 15th, 2017, 9:14 am 

Looking at the stocks of the company doing this, I see some optimism, but definitely cautious optimism. There's still a lot of weariness around gene therapies, not for ethical reasons, but for possibly disastrous unpredictable outcomes, some of which we've seen recently with CAR-T, which doesn't even do the editing inside the body (and for which Novartis charges half a million dollars!).
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Re: Altering human DNA

Postby SciameriKen on November 15th, 2017, 2:46 pm 

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Re: Altering human DNA

Postby zetreque on November 15th, 2017, 2:51 pm 

How concerned should we be about biological weapons with this technology?
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Re: Altering human DNA

Postby SciameriKen on November 15th, 2017, 3:19 pm 

zetreque » Wed Nov 15, 2017 6:51 pm wrote:How concerned should we be about biological weapons with this technology?



Referring to CRISPr technology? I wouldn't think that much - you would have to inject each person individually -- probably the bigger concern is this:

https://futurism.com/researchers-brough ... st-100000/
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Re: Altering human DNA

Postby BioWizard on November 15th, 2017, 4:19 pm 

zetreque » 15 Nov 2017 01:51 pm wrote:How concerned should we be about biological weapons with this technology?


As concerned as we are with technology in general. Or maybe a little lesss. Without some major advances, CRISPR would be one horribly inefficient weapon - compared to what’s already out there. And even then, it’s likely to be more “abusive” than murderous.
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